PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 10.99 |
PATENT ASSIGNEE | ZymoGenetics |
PATENT CLAIMS |
Method of producing GAD65; comprising culturing a methylo trophic yeast which grows on MeOH as a C & energy source, transformed with DNA construct which comprises following operatively linked elements - MeOH-inducible transcriptional promoter - DNA segment encoding GAD65 islet cell protein - Transcriptional terminator - Selectable marker in culture medium, whereby said GAD65 is produced at concn > 500 mg/L in culture medium |
PATENT PHOTOCOPY | Available on request |
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