PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 10.99 |
PATENT ASSIGNEE | ZymoGenetics |
PATENT CLAIMS |
Method for producing GAD65 protein; comprising culturing methylotrophic yeast which grows on MeOH as a C & energy source, transformed with DNA construct which comprises the following operatively linked elements - MeOH-inducible transcriptional promoter - DNA segment encoding GAD65 islet cell protein - Transcriptional terminator - Selectable marker in culture medium, whereby GAD65 protein is produced at concn > 500 mg/L in culture medium |
PATENT PHOTOCOPY | Available on request |
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