Main > GASTROENTEROLOGY > Ulcer > Non-Human Animal > Mongolian Gerbil > H pylori-Colonized Mongolian Gerbil > Prepn. Method. for > Anti-H pylori substance Screening

Product Japan. Y

PATENT ASSIGNEE'S COUNTRY Japan
UPDATE 07.99
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS Method of making a gerbil with gastric ulcer
- Obtaining Mongolian gerbil of an inbred line which is
deprived of food for 16-24 hours prior to adm of Helicobac
ter pylori
- Adm H. pylori to gerbil of (a) such that gastric ulcers deve
lop using an oral probe, said H. pylori being prepd by
method: Culturing H. pylori in a selective liquid nutrient
medium under microaerobic conditions for 24 hours such
that H. pylori is selected wherein said liquid medium is
selected from the group consisting of GC medium, Brucella
medium & brain heart infusion medium, further wherein said
liquid medium is supplemented with inactivated horse
serum
- Depriving the gerbil (b) of food & water for > 3 hours
after adm of H. pylori
- Maintaining gerbil (c) for > 6 months wherein the H. pylori
colonizes & forms gastric ulcer
PATENT PHOTOCOPY Available on request

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