Main > PROTEINS > Proteomics > Bacteria Proteomics > Mycobacterium tuberculosis > Protein > Autoimmune encephalomyelitis

Product Israel. Y

PATENT ASSIGNEE'S COUNTRY Israel
UPDATE 10.99
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS An isolated & purified protein derivable from the "Purified Protein Deriv." (PPD) of Mycobacterium tuberculosis (herein 12-kDa PPD protein), which protects mice against experimental autoimmune encephalomyelitis (EAE) & stimulates PPD-specific T lymphocytes, said isolated & purified protein having MW 12 kDa when analyzed by SDS-PAGE under reducing conditions, comprising the following AA seq. obtained by N-terminal analysis:
- Ala-Lys-Val-Asn-Ile-Lys-Pro-Leu-Glu-Asp-Lys-Ile-Leu-Val
Gln-Ala-Asn (residues 2-18 of SEQ ID NO:1)
& salts, functional deriv. & active fractions thereof which protect mice against EAE & stimulate PPD-specific T lymphocytes
PATENT PHOTOCOPY Available on request

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