Main > PROTEINS > Proteasome > Inhibition > Epoxomicin

Product USA. Y

CORP. SALE Epoxomicin = Epoxyketone
Six membered cyclic morpholino group is formed when the inhibitor interacts with the proteasome
MECHANISM OF ACTION Epoxomicin potently & irreversibly inhibits the chymotrypsin
like activity of the 20S proteasome, resulting in cell death, & it exhibits antitumor & anti-inflammatory activity in mice.
Epoxomicin does not inhibit other cellular proteases such as papain, chymotrypsin, trypsin, cathepsin B & calpain
UPDATE 03.00
AUTHOR This data is not available for free
LITERATURE REF. This data is not available for free

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