| CLASSIFICATION | CommPat |
| INDICATION'S | Co.'s major objective is to see if one can preserve the utility of already existent mainstream antibiotics by using them in combination with BPI |
| MECHANISM OF ACTION |
Two comp to anyibacterial activity - With gram-negative bacteria, BPI disrupts the outer membra ne - In second mechanism common to all bacteria, BPI interacts with the cytoplasmic membrane |
| PREPARATION | BPI is found in neutrophils (a type of white blood cell) |
| PRODUCER'S COUNTRY | USA |
| UPDATE | 04.00 |
| CONTACT | This data is not available for free |
| PATENT ASSIGNEE | This data is not available for free |
| PATENT CLAIMS |
Method of treat subject suffering from gram-positive bacterial infection by adm - Antibiotics selected from: Penicillins; Cephalosporins; Imipenem; Monolactams; Aminoglycosides; Tetracyclines Sulfonamides; Trimethoprim/sulfonamide; Fluoroquinolone Macrolides; Vancomycin; Polymyxins; Chloramphenicol & Lincosamides - The IMPROVEMENT comprising concurrently adm BPI protein prodt in amount effective to increase antibiotic su sceptibility of gram-positive bacterial species involved in the infection |
| PATENT PHOTOCOPY | Available on request |
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