Main > ORGANIC CHEMICALS > Aliphatics > Acids > DiHydroxy Acid > Dihydroxybutyric Acid > Alkyl Ester > Ketal-Protected Alkyl Ester > Synthesis

Product USA. W

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 12.99
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS - Treat carbohydrate substrate in solvent with H2O2 in presen
ce of base & subsequent acidification to afford mixt of
HO-CH2-CHOH-CH2-COOH (I) & glycolic acid
- Removing solvent to convert (I) to hydroxylated butyrolac
tone (II)
- Treat mixt contg (II) with R''-OH in presence of acid cata
lyst to afford: HO-CH2-CHOH-CH2-CO2R'' (III)
- Treat mixt contg (III) with -[C(R)(R')-](OR'')2 in presence of
acid catalyst
R,R' = 1-3C alkyl; R'' = 1-8C alkyl
PATENT PHOTOCOPY Available on request

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