PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 08.99 |
PATENT ASSIGNEE | Warner-Lambert |
PATENT CLAIMS |
- Treat HO-(CH2)n-C(Me)2-OH (n = 2-5) with P-CH2-Cl (P = styrene/divinylbenzene copolymer) in prsence of base & solvent to afford (I) - Treat (I) with 1,1'-carbonyldiimidazole in presence of base & solvent to afford (II) - Treat (II) seq with Me trifluoromethanesulfonate (MeOTf) & tert amine base in solvent to afford in situ (III) - Treat (III) to synthesize: P-CH2O-(CH2)n-C(Me)2-O-CO-Ami ne (IV) - Treat (IV) with acid in solvent to afford amine |
PATENT PHOTOCOPY | Available on request |
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