| PATENT ASSIGNEE'S COUNTRY | USA |
| UPDATE | 05.00 |
| PATENT ASSIGNEE | This data is not available for free |
| PATENT CLAIMS |
Method for identifying inhibitor of mutant ICE - Using a three-dimensional structure of ICE as defined by atomic coordinates of ICE according to FIG. 5 - Replacing > one of ICE's AA selected from 150 to 180, 236 to 240, 244 etc of SEQ ID NO:1 in said structure with a diffe rent naturally AA - Employing said structure to design potential inhibitor - Synthesizing inhibitor - Contacting inhibitor with mutant ICE in presence of substrate to test ability of inhibitor to inhibit ICE |
| PATENT PHOTOCOPY | Available on request |
|
Want more information ? Interested in the hidden information ? Click here and do your request. |