PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 06.00 |
PATENT ASSIGNEE | This data is not available for free |
PATENT CLAIMS |
Immunotoxin that does not require proteolytic activation for cytotoxic activity, said immunotoxin comprising - Pseudomonas exotoxin (PE) having amino & carboxyl ter minus, but lacking AA 1 to 279, & in which > half of domain Ib is replaced with - Part or all of either VL chain of Fv Ab fragment having amino & carboxyl terminus or VH chain of Fv Ab fragment having amino & carboxyl terminus, provided that if only a part of VL or VH chain is used, said part specifically binds to target molecule |
PATENT PHOTOCOPY | Available on request |
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