Main > MYCOLOGY. (FUNGI). > Inositol Phosphoryl Ceramide > Synthase > Assay

Product USA. U

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 02.00
PATENT ASSIGNEE University of Kentucky Research Foundation
PATENT CLAIMS Method to determine the ability of test compd to inhibit IPC synthase
- Recombinantly expressing the Saccharomyces IPC1 gene
in plurality of cells transformed to express said gene, said
cells being in homogeneous culture & located in a container
for addition of liquids
- Introducing excess ceramide & phosphatidylinositol, both
carrying label for identification & test compd to container
- Subjecting container & contents to conditions necessary
for ceramide conversion to phosphoinositol ceramide &
- Identifying those test compd which inhibit said conversion
PATENT PHOTOCOPY Available on request

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