PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 02.00 |
PATENT ASSIGNEE | University of Kentucky Research Foundation |
PATENT CLAIMS |
Method to determine the ability of test compd to inhibit IPC synthase - Recombinantly expressing the Saccharomyces IPC1 gene in plurality of cells transformed to express said gene, said cells being in homogeneous culture & located in a container for addition of liquids - Introducing excess ceramide & phosphatidylinositol, both carrying label for identification & test compd to container - Subjecting container & contents to conditions necessary for ceramide conversion to phosphoinositol ceramide & - Identifying those test compd which inhibit said conversion |
PATENT PHOTOCOPY | Available on request |
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