| PATENT ASSIGNEE'S COUNTRY | USA |
| UPDATE | 06.99 |
| INVENTOR | This data is not available for free |
| PATENT ASSIGNEE | This data is not available for free |
| PATENT CLAIMS |
Method of making a standardized prion prepn.: - Producing a plurality of transgenic mice having an ablated endogenous PrP gene & an exogenous PrP gene wherein the mice are susceptible to infection with prion which generally only infects a genetically diverse mammal, & further wherein the mice exhibit symptoms of prion disease within < 200 days after inoculation with prion which generally only infects a genetically diverse mammal - Inoculating the mice with compn comprising prions from genetically diverse mammal - Observing the mice until the mice exhibit symptoms of prion infection - Harvesting brain tissue from said mice - Homogenizing harvested brain tissue from mice to provide standardized prion prepn |
| PATENT PHOTOCOPY | Available on request |
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