CLINICAL STUDY | In animal trials, the researchers have shown, that the Ab block the effects of PCP for min. of 2 weeks. One month after a single adm. of the high-affinity Ab, brain concn of PCP in test animals remained reduced by 25% compared with untreated controls |
INDICATION'S | The Ab treat would be useful primarily for PCP addicts with a sincere desire to participate in their own therapy. If a few adm. could be given, then in a crisis situation, if something goes wrong in their life & they suddenly have the urge to go back & use the drug, this would give them time to get themselves back under control. Ab treat applicable to PCP addiction longer term treat |
MECHANISM OF ACTION |
The new Ab treat soaks up PCP in the bloodstream, preventing or at least minimizing its entry into the brain. The researchers believe the Ab treat significantly slows the "rush" an addict gets from taking PCP. "With the Ab one can reduce the speed at which it enters the brain. The Ab work by interacting with NMDA receptor system, a part of the brain associated with memory & learning. The Ab were designed to be a molecular mimic of PCP's NMDA receptor binding site. |
METHOD | Someone entering a treat program would get a single dose that might last 1-2 months, & if they should have a sudden urge to use a drug, or a relapse, it would blunt those effects or may be even block them, the researcher noted, extrapolating from animal studies to probable human effects |
OBSERVATION'S | PCP, or angel dust, not only gets people high, but also promotes psychotic & often violent behavior |
STATUS | Couple of years off |
TECHNOLOGY | Developed Ab as new form of medication for treat of PCP addiction |
UPDATE | 09.99 |
AUTHOR | This data is not available for free |
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