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Main.NEUROLOGY..Alzheimer's Disease.Beta Secretase [BACE1 (Abbrev.)].Aspartyl Protease 2 (Asp2)..Inhibitor..AntiSense OligoNucleotide.Patent.Claims Etc.Claim 1: A.Beta Cellular Productio.n from APP Redn Method: Transform.Cells In Vitro with AntiSense Reage.nt Capable of Reducing Asp2 Protein.Production by Redn Asp2 Transcripti.on in Cells; Whereas Said Redn..Correlates with Reduced Cellular.Processing of APP into Amyloid Beta.(A.Beta). Claim 2: Neural Cell..Claims 3,4: AntiSense Reagent Compr.ising Oligonucleotide Comprising.Single Stranded Nucleic Acid Seq..Capable of Binding to Hu-Asp mRNA.&/or Hu-Asp DNA resp. Assignee |