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Section:	Main.NEUROLOGY..Alzheimer's Disease.PreSenilin (Protein).PreSenilin-1..(Gamma Secretase).Mutated PreSenilin-1..Patent.Claims Etc.Claim 1: Isolated Mutant PreSenilin.-1 Polypeptide Comprise SEQ ID NO:5.; Residue 386 Selected: Threonine &.Residue 387 Selected: Glycine;.Mutant PS-1 Preferentially Modulate.Processing of APP to Yield Increase.d Levels of A.Beta.-1-42 Relative.to A.Beta-1-40 when Compared to.Wild Type PreSenilin-1 Polypeptide.Patent Assignee
Code:	63474
Product:	USA. P
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