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Section:	Main.NEUROLOGY..Alzheimer's Disease.Beta Secretase [BACE1 (Abbrev.)].Aspartyl Protease 2 (Asp2)..Patent.Claims Etc.Claim 1: Isolated Polynucleotide.SEQ ID NO: 7. Claim 2: Vector..Claim 3: Vector; Polynucleotide.Linked to Promoter to Promote.Expression Polypeptide Encoded.by Polynucleotide in Host Cell.Claim 4: Host Cell Transformed with.Vector (Cl. 3). Claim 5: Mammalian.Cell. Claim 6: Cl. 4 Host Cell.Expresses Polypeptide on Surface.Claim 7: Host Cell (Cl. 4) Transfec.ted with Nucleic Acid Comprising.Nucleotide Seq. Encodes APP.Includes 2 Carboxy-Terminal Lysine.Residues. Claim 8: Host Cell (Cl. 7.) Expresses Polypeptide & APP on.Surface. Claim 9: Murine Asp2.Polypeptide Make Method:.Culturing Host Cell (Cl. 4) in.Culture Medium. Claim 10:.Purifying Polypeptide from Cell..Claim 14: Idem to Cl. 7 Except."After APP": or Fragment Thereof.Contg. Beta-Secretase Cleavage Site.Claim 16: Host Cell (Cl. 14); APP.Comprises Swedish Mutation.(K.fwdarw.N, M.fwdarw.L) Adjacent.to the Beta-Secretase Cleavage Site.Patent Inventors
Code:	63472
Product:	Sweden. USA. BGHPY
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